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Istradefylline 40 mg/working day greater peak degrees and AUC of CYP3A4 substrates in scientific trials. This impact wasn't observed with istradefylline 20 mg/working day. Think about dose reduction of sensitive CYP3A4 substrates.You shouldn't use this drugs If you're allergic to doxepin, amoxapine, or loxapine, or In case you have:ferric maltol, t